青云英语翻译

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翻译结果1翻译结果2 翻译结果3翻译结果4翻译结果5

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氟吡汀引起的剂量依赖性减少NMDA受体介导的谷氨酸诱导的上升,细胞内Ca + +浓度的影响。

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氟吡汀导致剂量依赖性减少的 NMDA 受体介导谷氨酸诱导细胞内 Ca + + 浓度上升。它将绑定到并激活 G 蛋白偶联内心整流 K + 通道。此通道的激活会导致神经元膜的超极化和神经元变得不那么容易激动 ;因此,有休息的神经元膜的稳定。激活此通道的毒品被称为选择性神经元钾通道开放剂 (SNEPCO) 和氟吡汀是原型。实验证据表明,氟吡汀可能通过充当氧化剂 NMDA 受体的氧化还原现场的压制通道开放。这一行动抑制痛觉冲动在神经元励磁期间的传输。

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Flupirtine在细胞内Ca++集中导致NMDA感受器官斡旋的谷氨酸导致的上升的药量依赖减少。它束缚对并且激活被结合的G-蛋白质在内部矫正K+渠道。

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